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In some situations, these issues are exacerbated by fungal toxins linked to chronic candidiasis and mold-produced compounds. For example, chemical aldehydes from fungus are known to be highly reactive compounds that […]":1,"#Posted on <time ljsid-1=\"\">August 2, 2021</time>":1,"#<a ljsid-0=\"\">\"Healing from Rheumatoid Arthritis\" by Dr. Woeller</a> from <a ljsid-2=\"\">Mosaic Diagnostics</a> on <a ljsid-4=\"\">Vimeo</a>.":1,"#William Shaw, PhD provides information about ways to detoxify the body and what tests can determine how well a patient is able to detoxify. Includes case studies and discussion about reference range percentiles.":1,"#Guidelines for the treatment of yeast have been documented in the literature for nearly every major organ system (Pappas). Yet, a standard of care for gastrointestinal yeast treatment is surprisingly absent despite the large body of work demonstrating that pathogenic yeast causes harm to various aspects of the gastrointestinal tract (Zwolinska, Brzozowski). Clinicians suspicious of […]":1,"#Greenblatt Book":1,"#Solving the Brain Puzzle LP":1,"#Employee Handbook":1,"#New Client Form USA and Canada":1,"#Altri fattori":1,"#Trasformazione dei prodotti alimentari":1,"#Are you interested in understanding the role of integrative medicine in mental health? This informative webinar provides an introduction to integrative approaches in mental health care. Dr. Greenblatt provides an overview of the principles and practices of integrative medicine, which incorporates conventional and complementary therapies to address the physical, mental, emotional, and spiritual aspects of […]":1,"#Join us for a compelling webinar on the topic of mitochondrial dysfunction and autism, as we revisit the latest research and findings in this field. Learn about the role of mitochondria in cellular energy production and how dysfunction in these crucial cellular powerhouses may contribute to the development of autism spectrum disorders. Gain insights from […]":1,"#Posted on <time ljsid-1=\"\">November 9, 2023</time>":1,"#The Role of Vitamin D, Serotonin and Melatonin Balance in Adrenal Dysfunction — Great Plains Laboratory":1,"#Mosaic Diagnostics Iron + Total Iron-Binding Capacity Sample Test Report":1,"#Ted Page, PhD, and Mary Coleman, MD, have established that abnormalities of purine and pyrimidine metabolism are common in children with autism and PDD. These abnormalities began to be reported over 30 years ago, but progress has been hampered because only a small number of laboratories performed these tests and these laboratories performed testing on a very sporadic basis. The children with these genetic diseases have many or all of the classic symptoms of autism and therefore cannot easily be distinguished from “typical” children with autism. A critical finding of Page and Coleman is that two major subtypes of this disorder can be distinguished by a simple clinical test of urine, which is the content of uric acid.":1,"#I became interested in the role of these compounds after noticing that a significant number of children with autism had high amounts of the compound uracil in the urine tested with the Organic Acids Test in our laboratory. The upper limit of normal is 22 mmol/mol creatinine but we found that one child with autism had a value of 360 mmol/mol creatinine and perhaps 15% of all children with autism had elevated values to a lesser degree. This was a very interesting finding since there is an inborn error of metabolism called dihydropyrimidine dehydrogenase deficiency in which both uracil and thymine are elevated in the urine. Some of the individuals with this disorder had autistic symptoms. However, the individuals with the abnormality of uracil detected in The Great Plains Laboratory invariably had normal or very slightly elevated values for thymine in the urine. Therefore, I assumed they didn’t have dihydropyrimidine dehydrogenase deficiency. However, Ted Page suggested to me that these individuals might have a form of enzyme deficiency in which thymine could be processed by the enzyme but uracil could not. This is an area of great interest and The Great Plains Laboratory will be involved in developing an enzyme test for this abnormality that can be done on blood.":1,"#The Omega 3 Test also supplies information regarding important omega fat ratios. Specifically tested are the omega 6:3 and AA:EPA ratios. Ideally, both ratios should be low. As we saw above, the balance between omega 6 and 3 fats is crucial in many disease states. The Omega 6: 3 ratio in the developed world tends to be much higher than optimal health would support. This is due to the abundance of omega 6 rich foods in the diet. Concurrently, there is a substantial lack of omega 3s in the diet. Common foods like chips, snack cakes, and fast foods are readily available and cooked in oils high in omega 6. When improperly balanced with omega 3s an environment of inflammation is created. On average the ratio seen in most individuals is upwards of 15-17:1 and higher results have been documented. In asthma, a ratio of 5:1 correlates with decreased airway inflammation and improved clinical outcomes (<a ljsid-1=\"\">19</a>). In contrast, a ratio of 2-3:1 was helpful in RA. 10:1 ratio was seen as detrimental in both conditions. The differences in ratios for each condition opens the thought process that the ratio optimization will depend on the condition and also the level in which the client in question is currently trending. Testing is the best way to understand where each client’s ratio stands pre-treatment.":1,"#Research has shown great benefits in omega 3 supplements as an addition to various disease states. Most common omega fats have been studied in reducing the incidence of cardiovascular events. Most of the research is focused on the reduction of total cholesterol. Omega 3 fats have been shown to reduce LDL-C and triglycerides, which are implicated in cardiovascular events (<a ljsid-1=\"\">5</a>). The addition of alpha-linolenic acid (ALA) has shown promising results in reducing the incidence of arrhythmias (<a ljsid-3=\"\">3</a>). In relation to mental health, omega fats are often seen to be reduced in the blood of those diagnosed with schizophrenia. Various mechanisms are thought to play a role in the reduction of omega 3s, especially DHA. The level of DHA in mental health is crucial to understand as 60% of the brain is constituted of phospholipids and 40% of those are DHA. This is often deficient in schizophrenic patients. In some cases, it’s a genetic misincorporation of DHA as there is a fatty acid binding protein preference for more in inflammatory omega 6 fatty acids (<a ljsid-5=\"\">7</a>). This leads to an increased omega 6:3 ratio. In most cases, these patients have been noted to eat a more inflammatory diet, devoid of omega 3 rich foods (<a ljsid-7=\"\">14</a>). In depression, the addition of omega DHA and EPA has been shown to improve mood. This is also seen in perinatal and postpartum depression when given in combination with other traditional therapies. In Autism Spectrum Disorders, blood levels of fatty acids show increased omega 6 PUFA in comparison to omega 3. This equates to an elevated omega 6:3 ratio (<a ljsid-9=\"\">12</a>). More studies with larger sample sizes are needed to further the research in autism even though many clinical benefits have been seen with omega fat administration (<a ljsid-11=\"\">1</a>).":1,"#Omega Fats and Common Conditions":1,"#January 17, 2022":1,"#In today’s developed and developing worlds, inflammation is on the rise. Inflammation is a protective mechanism employed by our bodies when being attacked or under stress. Acutely, inflammation is protective. Chronic inflammation is what contributes to long-standing chronic disease. With the ease of eating on the go and the abundance of fast food, foods that […]":1,"#Clostridia Archives - MosaicDX":1,"#Tag: <span ljsid-1=\"\">Clostridia</span>":1,"#In this informative webinar, Dr. Woeller explores the link between neurotransmitter imbalances and the Organic Acids Test (OAT). Gain a deeper understanding of how OAT results can provide valuable insights into the functioning of neurotransmitters in the body, and how imbalances in these chemical messengers can impact mental health, mood, cognition, and behavior. Discover the […]":1,"#Posted on <time ljsid-1=\"\">February 27, 2024</time>":1,"#Metals – Toxic + Nutrient Elements – Hair:":1,"#Propriétés et métabolisme des mycotoxines, <a ljsid-1=\"\">partie 1</a> et <a ljsid-3=\"\">partie 2</a> .":1,"#Teil zwei":1,"#The webinar will provide an overview of the latest research on the use of phytochemicals in the management of depression, including their mechanisms of action, safety, and efficacy. It will also discuss practical applications of phytochemicals in clinical practice, including dosages, formulations, and potential interactions with other medications.":1,"#This insightful webinar explores the complex relationship between viral infections, brain inflammation, and autism. Expert in the field, Dr. Woeller, will discuss the current research and evidence linking viral infections to autism spectrum disorder (ASD), including the potential mechanisms by which viral infections may trigger or exacerbate brain inflammation in individuals with ASD. You’ll gain a deeper understanding of how viral infections can impact brain health and contribute to the development and progression of autism. He will also discuss the role of the immune system, the gut-brain axis, and environmental factors in the interplay between viral infections and ASD. Additionally, you’ll learn about potential therapeutic strategies to mitigate the effects of viral infections on brain inflammation and improve the health and well-being of individuals with autism. Whether you are a healthcare professional, a parent, a caregiver, or simply interested in learning more about the connection between viral infections, brain inflammation, and autism, this webinar is a valuable resource for you. Don’t miss out on this opportunity to expand your knowledge and gain insights into this important topic!":1,"#Tag: <span ljsid-1=\"\">DNA Methylation</span>":1,"#Negative Feedback Loop":1,"#Glutathione Production":1,"#Pyroglutamic Acid":1,"#December 21, 2020":1,"#When evaluating marker 58 on the OAT, elevations give insight to how upregulated the glutathione cycle is at the moment of testing. In instances of true elevations, out of the reference range, there is clear glutathione deficiency. It can be said that the person’s body is struggling to make adequate glutathione. In situations like this all aspects of the client’s health presentation and medications/supplements should be evaluated. Certain pharmaceuticals, like large amounts or regular small doses of acetaminophen, which is known for its hepatotoxicity, stimulate the need for more glutathione. This is especially significant when people are taking multiple pharmaceuticals that may be liver toxic and have a cumulative effect. Other things that deplete glutathione include alcohol, recreational drug use, a fructose rich diet, the natural aging process, prolonged fasting (24 hours or longer), and anything that causes increases in oxidative stress. If this has been ruled out as the cause of elevations in pyroglutamic acid, then toxic exposures can be assessed. As stated, glutathione production is upregulated during a toxic exposure. Since the body upregulates glutathione for various reasons, it’s hard to pinpoint which toxin test to perform. It could be heavy metals, non-metal toxins, mold toxins, or a combination. Consider running Mosaic Diagnostics offered profiles: <a ljsid-1=\"\">MycoTOX</a>, <a ljsid-3=\"\">GPL-TOX</a>, <a ljsid-5=\"\">Heavy Metal Testing</a>.":1,"#During this process, as glutathione is produced, there is a negative feedback loop. When in abundant supply, glutathione inhibits the gamma-glutamyl cysteine synthetase enzyme. This blocks the combining of cysteine and glutamate before being joined with glycine to form more glutathione. This is the body’s way of regulating the amount of glutathione in the system. In times of oxidative stress, toxic exposure, inflammation, etc the glutathione production cycle is upregulated due to an increased need for glutathione to protect the body. When glutathione is deficient, the negative feedback loop is dysregulated allowing for more cysteine to be joined in the production of more glutathione. Since the regulation is no longer happening the entire cycle of production is upregulated. Thus, there is also an upregulation of 5-oxoproline being converted into glutamate. Because the enzyme, 5-oxoprolinase, is ATP dependent and the rate limiting enzyme of the whole cycle there becomes a buildup in pyroglutamic acid. This is because the need for glutathione production, in times of stress and toxicity, outweighs the rate in which 5-oxoprolinase can transform 5-oxoproline into glutamate. So, 5-oxoproline builds up leading to elevated urinary values of pyroglutamic acid. Also, due to the ATP dependent nature of the enzyme, energy depletion is seen and stimulates the expression of energy depletion symptoms.":1,"#Available in Spanish, Portuguese":1,"#View All Workshops":1,"#Download All Slides and Resources":1,"#Join us for a comprehensive webinar on IgG food sensitivity and its impact on health and disease. We will delve into the science behind IgG food sensitivities, how they can trigger inflammation and immune responses in the body, and the link between IgG food sensitivities and various diseases. You’ll learn about the latest research on how IgG food sensitivities can contribute to conditions such as gastrointestinal disorders, autoimmune diseases, skin conditions, migraines, and more. We will discuss testing methods for identifying IgG food sensitivities, interpretation of results, and practical strategies for incorporating IgG food sensitivity testing and management into clinical practice. You’ll also gain insights into integrative treatment approaches for addressing IgG food sensitivities, including elimination diets, targeted nutritional interventions, and lifestyle changes. Whether you are a healthcare professional or an individual interested in understanding the role of IgG food sensitivities in disease, this webinar is a valuable resource for you. Join us to expand your knowledge and learn practical strategies for addressing IgG food sensitivities in clinical practice!":1,"#Join us for a comprehensive webinar on IgG food sensitivity and its impact on health and disease. We will delve into the science behind IgG food sensitivities, how they can trigger inflammation and immune responses in the body, and the link between IgG food sensitivities and various diseases. You’ll learn about the latest research on […]":1,"#IgG Food Sensitivity and Disease — Great Plains Laboratory":1,"#Answers to Anorexia":1,"#This concludes the evaluation of each mycotoxin on the <a ljsid-1=\"\">Profil MycoTOX</a>. Hopefully, it helps in the understanding of these mycotoxins in nature, and potentially in our bodies.":1,"#As a mycotoxin classified under the Aspergillus category, <strong ljsid-1=\"\">Gliotoxine</strong> has an average elevation range for people who are suspicious of mycotoxins between 200-2000 ng/g of creatinine. More extreme cases have been shown to be in the 20,000-25,000 ng/g of creatinine range. Although Aspergillus (particularly the fumigatus species) and Penicillium have been shown to produce Gliotoxin, some yeast can as well, particularly <a ljsid-3=\"\">Candidose</a> (1). A study that looked at A. fumigatus strains from silos contaminated with mold found only 11% of the cultures to be gliotoxin producers (2). On the other hand, a study performed at <a ljsid-5=\"\">MD Anderson Cancer Center</a>, found 93% of A. fumigatus strains from respiratory and tissue samples produced gliotoxin (3). Other studies that compared environmental versus clinical A. fumigatus producing gliotoxin, have not only found geographical variations, but overall as the evidence suggests, it is found more commonly as the result of internal colonization rather than contaminated environmental sources (4). Gliotoxin is also commonly found in the soil, but in that case, it is most commonly produced by Trichoderma virens to support competition among the other fungus and bacteria (4).":1,"#Both <strong ljsid-1=\"\">Roridin E</strong> et <strong ljsid-3=\"\">Verrucarin A</strong> mycotoxins categorized under the Stachybotrys mold, are relatively similar, though differences will be discussed as they arise. Roridin E is produced by Fusarium, Myrothecium, Trichothecium, Stachybotrys, and less commonly, the Betula cordifolia (the mountain paper birch tree) and the Podostroma cornu-damae mushroom (20, 21). Verrucarin A is also produced by Fusarium, Myrothecium, Trichoderma, and Stachybotrys, but differs in that Trichothecium, Cephalosporium, and Verticimonosporium can also produce it. Though not as common to come up positive on the testing, these are some of the more toxic mycotoxins measured. When exposed to trichothecenes the effects can be quite toxic. For Roridin E; irritation of the skin, mucosal layers of the intestines, and the nasal passage have been observed, sometimes leading to blisters and bleeding. Ocular symptoms have been described as burning, blurred vision, conjunctivitis, and pain. Hypotension, nausea, vomiting, and potentially shock have also been documented (22). Symptoms can be variable for Verrucarin A, but can be extreme and have cascading effects. The symptoms include bone marrow damage, nervous disorders, cardiovascular alterations, hemostatic derangements, immunodepression, gastric inflammation and lesions, anorexia, and dermatological lesions potentially leading to necrosis (23,24).":1,"#Similar in structure to aflatoxins, particularly B1 (15), <strong ljsid-1=\"\">Sterigmatocystin (ST)</strong> is most commonly produced by <em ljsid-3=\"\">Penicillium</em> et <em ljsid-5=\"\">Aspergillus</em> (mainly <em ljsid-7=\"\">A. Versicolor and A. nidulans</em>), but can also be produced by <em ljsid-9=\"\">Fusarium</em>, <em ljsid-11=\"\">Bipolaris</em>and even <em ljsid-13=\"\">Stachybotrys</em> and Chaetomium (16, 17). It is not currently monitored in food due to the lack of occurrence. Stored cheese and grains are the only documented contaminated circumstances and there have been no outbreaks associated with ST reported to date (16). It is mostly associated with being a potent liver carcinogen (18). The data was limited on ST, and information was difficult to obtain.":1,"#Stérigmatocystine<strong ljsid-1=\"\"> (ST)</strong>":1,"#Del":1,"#Tilmeld":1,"#Mere…":1,"#In assessment of the Organic Acid Test (OAT), a beneficial section is the “Indicators of Detoxification,” The first marker found in this section, marker 58, gives insight into detoxification and glutathione synthesis. As this marker increases, it can guide practitioners to the possibility of toxic exposure being a piece to the client’s clinical picture. In […]":1,"#In this recorded webinar, expert in the field, Dr. Woeller, shares 10 compelling reasons why every individual with a special needs diagnosis should consider undergoing an Organic Acids Test (OAT). From autism spectrum disorder (ASD) to developmental delays, ADHD to mitochondrial dysfunction, the OAT can provide valuable insights into metabolic and biochemical imbalances that may […]":1,"#10 Reasons Every Individual With A Special Needs Diagnosis Should Do An Organic Acids Test — Great Plains Laboratory":1,"#In this recorded webinar, expert in the field, Dr. Woeller, shares 10 compelling reasons why every individual with a special needs diagnosis should consider undergoing an Organic Acids Test (OAT). From autism spectrum disorder (ASD) to developmental delays, ADHD to mitochondrial dysfunction, the OAT can provide valuable insights into metabolic and biochemical imbalances that may contribute to a wide range of special needs conditions. Learn how the OAT can help uncover underlying root causes of symptoms, such as nutrient deficiencies, neurotransmitter imbalances, oxidative stress, detoxification issues, and more. Discover the clinical utility of OAT in guiding personalized treatment strategies for individuals with special needs, and gain practical tips on how to interpret and integrate OAT results into clinical practice. Access this recorded webinar now to learn why the Organic Acids Test is a valuable tool for individuals with special needs and how it can inform targeted interventions to optimize health and well-being.":1,"#Metabolism does slow with age, but recent research suggests that it peaks earlier and slows later than we’ve thought. There appears to be a gradual decline between ages 20 and 60, with the more significant change happening in the elder years.<sup ljsid-1=\"\">2</sup>":1,"#You might remember a time in your life when you could seemingly eat whatever you wanted and not gain a single pound. Those days may feel long gone now.":1,"#METABOLISM CHANGES":1,"#Researchers suggest these feelings are usually related to lack of sleep, poor nutrition, stress, or medications. Furthermore, brain fogginess may be tied to low-grade inflammation.<sup ljsid-1=\"\">1 </sup>While there may not be specific clinical treatments for brain fog, addressing underlying inflammation is the best approach.":1,"#Getting older comes with common complaints like a foggy brain, slowed metabolism, and changes in body composition. Learn how to feed your brain and boost your metabolism no matter what season of life you’re in.":1,"#How to Feed Your Brain & Boost Your Metabolism - MosaicDX":1,"#OAT Logo":1,"#The term “brain fog” is used broadly to describe a feeling of cloudiness, forgetfulness, or trouble concentrating. This can make it difficult to get things done.":1,"#Lauren specializes in plant-based living and vegan and vegetarian diets for all ages. She also enjoys writing about parenting and a wide variety of health, environmental, and nutrition topics. Find her at <a ljsid-1=\"\">www</a><a ljsid-2=\"\">.laurenpanoff.com</a>.":1,"#Chen X, Huang Y, Cheng HG. Lower intake of vegetables and legumes associated with cognitive decline among illiterate elderly Chinese: a 3-year cohort study. <em ljsid-1=\"\">J Nutr Health Aging.</em> 2012;16(6):549-552. doi:10.1007/s12603-012-0023-2":1,"#Hu Y, Ding M, Sampson L, et al. Intake of whole grain foods and risk of type 2 diabetes: results from three prospective cohort studies. <em ljsid-1=\"\">BMJ</em>. 2020;370:m2206. Published 2020 Jul 8. doi:10.1136/bmj.m2206":1,"#von Schacky C. Importance of EPA and DHA Blood Levels in Brain Structure and Function. <em ljsid-1=\"\">Nutrients</em>. 2021;13(4):1074. Published 2021 Mar 25. doi:10.3390/nu13041074":1,"#La Fata G, Weber P, Mohajeri MH. Effects of vitamin E on cognitive performance during ageing and in Alzheimer’s disease. <em ljsid-1=\"\">Nutrients</em>. 2014;6(12):5453-5472. Published 2014 Nov 28. doi:10.3390/nu6125453":1,"#Kalt W, Cassidy A, Howard LR, et al. Recent Research on the Health Benefits of Blueberries and Their Anthocyanins. <em ljsid-1=\"\">Adv Nutr. </em>2020;11(2):224-236. doi:10.1093/advances/nmz065":1,"#Morris MC, Wang Y, Barnes LL, Bennett DA, Dawson-Hughes B, Booth SL. Nutrients and bioactives in green leafy vegetables and cognitive decline: Prospective study. <em ljsid-1=\"\">Neurology</em>. 2018;90(3):e214-e222. doi:10.1212/WNL.0000000000004815":1,"#Kim J. Pre-Clinical Neuroprotective Evidences and Plausible Mechanisms of Sulforaphane in Alzheimer’s Disease.<em ljsid-1=\"\"> Int J Mol Sci.</em> 2021;22(6):2929. Published 2021 Mar 13. doi:10.3390/ijms22062929":1,"#Keller K, Engelhardt M. Strength and muscle mass loss with aging process. Age and strength loss. <em ljsid-1=\"\">Muscles Ligaments Tendons J. </em>2014;3(4):346-350. Published 2014 Feb 24.":1,"#Pontzer H, Yamada Y, Sagayama H, et al. Daily energy expenditure through the human life course. <em ljsid-1=\"\">Science</em>. 2021;373(6556):808-812. doi:10.1126/science.abe5017":1,"#BRAIN FOG":1,"#Kverno K. Brain Fog: A Bit of Clarity Regarding Etiology, Prognosis, and Treatment. <em ljsid-1=\"\">J Psychosoc Nurs Ment Health Serv.</em> 2021;59(11):9-13. doi:10.3928/02793695-20211013-01":1,"#We will all experience changes in our everyday wellness, but that doesn’t mean we always have to accept it as a new normal. While not everything is preventable, improving your nutrition and exercise routine can make a significant difference in your brain and metabolic health. Consider a Mosaic Diagnostics laboratory test to gain further insight, and always speak to your healthcare provider if you have health concerns.":1,"#TAKING BRAIN AND METABOLIC HEALTH INTO YOUR HANDS":1,"#Organic acids are chemical compounds that are products of metabolism and are excreted in the urine. The Organic Acids Test (OAT) utilizes 76 markers to offer a <a ljsid-1=\"\">comprehensive metabolic snapshot</a> of overall health. This includes evaluating the balance of intestinal microorganisms that can contribute to numerous health concerns. The OAT also includes markets for oxidative stress, neurotransmitter levels, oxalates, vitamins, and minerals that may be correlated with certain conditions.":1,"#OAT (ORGANIC ACID TEST)":1,"#This is a urine test that <a ljsid-1=\"\">offers information</a> about metabolic, nutritional, and neurological disorders. It analyzes 40 amino acids, identifies abnormalities, and provides potential causes, consequences, and nutrition-related information. This test may be insightful for those experiencing things like mood changes, tiredness, and feelings of fogginess.":1,"#AMINO ACID TEST":1,"#In addition to improving your nutrition and exercise habits, consider a diagnostic test to gain further insight into your health. Below are two of the tests offered by Mosaic Diagnostics and what data they can provide.":1,"#CONSIDER A DIAGNOSTIC TOOL":1,"#<strong ljsid-0=\"\">Legumes:</strong> Soy foods, like tofu and tempeh, as well as beans, peas, and lentils, are rich in B vitamins and flavonols, which help support brain health. One study found that diets low in legumes were associated with more cognitive decline among the elderly.<sup ljsid-2=\"\">10</sup>":1,"#Countless adults experience things like brain fogginess, a slowed metabolism, and a loss of muscle mass. Let’s take a deeper dive into these common complaints and what you can do to feed your brain and metabolism well.":1,"#<strong ljsid-0=\"\">Whole grains: </strong>Contrary to their ultra-refined counterparts, whole grains maintain all the original parts of the grain, including fiber, vitamins, and minerals. These help promote satiety and stable blood sugar, benefiting mood and energy levels.<sup ljsid-2=\"\">9</sup>":1,"#<strong ljsid-0=\"\">Fatty fish or algae oil: </strong>These provide the omega-3 fats EPA and DHA, which help support brain health and function.<sup ljsid-2=\"\">8</sup>":1,"#<strong ljsid-0=\"\">Nuts and seeds: </strong>Almonds, pistachios, cashews, walnuts, chia, flax, and hemp seeds, for example, contain unsaturated fatty acids and vitamin E, which acts as a protective antioxidant.<sup ljsid-2=\"\">7</sup>":1,"#<strong ljsid-0=\"\">Colorful berries:</strong> An array of blueberries, strawberries, and raspberries provide antioxidants that help support cellular health by protecting the body from oxidative stress-related damage.<sup ljsid-2=\"\">6</sup>":1,"#<strong ljsid-0=\"\">Leafy greens:</strong> This includes foods like lettuce, spinach, arugula, chard, and fresh herbs. One study among 60-90-year-olds found that those who ate at least one serving of leafy greens per day experienced brain function equivalent to being 11 years younger.<sup ljsid-2=\"\">5</sup>":1,"#<strong ljsid-0=\"\">Cruciferous vegetables: </strong>Add more broccoli, Brussels sprouts, cauliflower, and kale to your plate. Broccoli contains a compound called sulforaphane, which has been widely studied for its brain-protective and health-promoting characteristics.<sup ljsid-2=\"\">4</sup>":1,"#Consider adding more of these foods to feed your brain and metabolism:":1,"#Instead, focus on minimally processed foods, especially fruits, vegetables, nuts, seeds, grains, and legumes. These provide fiber, antioxidants, vitamins, minerals, unsaturated fats, and protein your body and brain need. These nutrients help support normal blood sugar regulation, a normal inflammatory response, and a healthy brain, mood, and metabolism.":1,"#While it’s easy to eat mostly packaged and convenience foods today, these tend to be nutrient-poor, high in calories, fat, sodium and added sugar, but low in vitamins and minerals. As a result, they often encourage unstable blood sugar, brain fog, tiredness, low mood, inflammation, and weight gain, all of which have negative effects on your feelings of wellness.":1,"#What you feed your brain and body every day is key to your health. Nutrition determines how much fuel you have and how well your body can perform and protect you from ailments and injuries.":1,"#As we age, changes in our normal standard of health can become more noticeable. Ever walked into a room and forgotten what you came for, woken up groggy for no reason, or noticed unintentional changes in body composition? These can all be frustrating to experience but are more common than you may think.":1,"#Staying active helps support mobility, energy, healthy metabolism, and body composition. Consider the ways you already enjoy moving your body, things you’re interested in trying, and how you can incorporate more strength training exercises, like using resistance bands, dumbbells, or bodyweight movements.":1,"#Regular exercise with intentional rest days is ideal for overall wellness. Rotating activities like jogging, walking, swimming, biking, sports, yoga, stretching, and resistance or strength training engages your full body, promote muscle building and maintenance, and offer overall health benefits.":1,"#PHYSICAL ACTIVITY":1,"#Now that we’ve covered some of the most frequent brain and metabolism-related complaints among adults, let’s examine how you can adjust your lifestyle to improve them. Two of the biggest factors in feeding your brain well and supporting a healthy metabolism are exercise and nutrition.":1,"#HOW TO FEED YOUR BRAIN AND BOOST YOUR METABOLISM":1,"#It also helps you burn the excess fat that could otherwise increase the risk of heart disease and other health problems. Furthermore, having muscle increases your strength and ability to engage in physical activities you enjoy.":1,"#Maintaining a healthy percentage of muscle mass helps reduce further age-related muscle loss from occurring. Muscle is also responsible for determining your basal metabolic rate, or how many calories you burn each day.":1,"#Loss of muscle mass starts around age 30.<sup ljsid-1=\"\">3</sup> Regardless of how old you are, now is an important time to start focusing on ways to preserve existing lean muscle mass and build more.":1,"#REDUCED MUSCLE MASS":1,"#What’s more likely contributing to perceived changes in metabolism during adulthood are our lifestyle habits, particularly exercise, and nutrition. These play a large role in energy expenditure, as well as feeling able to participate in things we enjoy.":1,"#May 9, 2023":1,"#Michael J. Lumb and Christopher J. Danpure. Functional Synergism between the Most Common Polymorphism in Human Alanine:Glyoxylate Aminotransferase and Four of the Most Common Disease-causing Mutations. Journal of Biological Chemistry Vol. 275, No. 46, November 17, pp. 36415–36422, 2000":1,"#Konstantynowicz J, Porowski T, Zoch-Zwierz W, Wasilewska J, Kadziela-Olech H, Kulak W, Owens SC, Piotrowska-Jastrzebska J, Kaczmarski M. A potential pathogenic role of oxalate in autism. Eur J Paediatr Neurol. 2012 Sep;16(5):485-91.":1,"#Learn about the critical role of mitochondrial dysfunction in autism and its negative impact on health in this comprehensive webinar. We will delve into the science behind mitochondrial dysfunction, including its relationship with autism spectrum disorder (ASD), and explore how it can affect various aspects of health, such as energy production, immune function, gastrointestinal health, […]":1,"#Mitochondrial Dysfunction and Autism: Understanding The Negative Impact It Has On Health and What You Can — Great Plains Laboratory":1,"#Learn about the critical role of mitochondrial dysfunction in autism and its negative impact on health in this comprehensive webinar. We will delve into the science behind mitochondrial dysfunction, including its relationship with autism spectrum disorder (ASD), and explore how it can affect various aspects of health, such as energy production, immune function, gastrointestinal health, and cognitive function. You’ll gain a deep understanding of the connection between mitochondrial dysfunction and autism, as well as practical strategies for identifying and addressing mitochondrial dysfunction in individuals with ASD. Topics covered will include the science of mitochondrial dysfunction, common signs and symptoms, diagnostic tools and testing, and integrative therapies for improving mitochondrial health. Don’t miss this opportunity to enhance your knowledge and skills in addressing mitochondrial dysfunction in individuals with autism.":1,"#Understanding Alzheimer’s Disease and Dementia According to the Alzheimer’s Foundation of America, Alzheimer’s disease is a progressive, degenerative disorder that attacks the brain’s nerve cells (neurons), resulting in loss of memory, cognitive and language skills, and behavioral changes. These neurons produce the neurotransmitter (brain chemical), acetylcholin, and break connections with other neurons and ultimately die. […]":1,"#O uso de AOs evoluiu da investigação do EIM para o fornecimento de informações sobre desequilíbrios metabólicos funcionais.":1,"#oA avaliação destes produtos a jusante das vias metabólicas fornece informações sobre <em ljsid-1=\"\">potenciais deficiências nutricionais, inflamação, toxicidade e outros desequilíbrios que podem estar contribuindo para</em> <em ljsid-3=\"\">queixas clínicas</em>":1,"#potenciais deficiências nutricionais, inflamação, toxicidade e outros desequilíbrios que podem estar contribuindo para":1,"#This time only, Dr. Lawrence has given special permission for access to the presentation slides. Download the PDF slides. The material contained within this presentation is not intended to replace the services and/or medical advice of a licensed healthcare practitioner, nor is it meant to encourage diagnosis and treatment of disease. It is for educational […]":1,"#This time only, Dr. Lawrence has given special permission for access to the presentation slides. <a ljsid-1=\"\">Download the PDF slides.</a>":1,"#Posted on <time ljsid-1=\"\">April 24, 2020</time>":1,"#We’re committed to enhancing your experience, every step of the way. MosaicDX Portal Enhanced Drop-Ship Ordering Experience Effective: 1/8/2024 We’ve introduced enhancements to streamline the drop-shipping process, simplifying your practice’s data entry and optimizing the point in the process where patients verify their address and make payments for their labs. Enhancements for Practitioner Save Valuable […]":1,"#MosaicDX Updates":1,"#April 24, 2020 Detoxification, MycoTOX Do you ever walk into a room in your home or office building and notice a faint odor? Or have you or someone you love had the unfortunate experience of a chronic condition that isn’t easily explained after consulting with various doctors? Well, mold toxicity could be a major factor in […]":1,"#Do you ever walk into a room in your home or office building and notice a faint odor? Or have you or someone you love had the unfortunate experience of a chronic condition that isn’t easily explained after consulting with various doctors? Well, mold toxicity could be a major factor in your clinical picture. So […]":1,"#In this informative webinar, Dr. Woeller presents compelling case studies that highlight the importance of adrenal hormone testing and treatment in clinical practice. Through real-world cases, he shares practical insights on interpreting adrenal hormone test results, identifying adrenal dysfunction, and designing personalized treatment plans. Discover how adrenal hormone imbalances can impact patients’ health and wellbeing, […]":1,"#nobody@mycraftmail.com":1,"#Chai W, Liebman M. Effect of different cooking methods on vegetable oxalate content. J Agric Food Chem. 2005;53(8):<a ljsid-1=\"\">3027-3030</a>. doi:10.1021/jf048128d":1,"#How to know when to suggest a diet like SCD, GAPS or Paleo for your patients: Have clinical tests like our Organic Acids Test or Microbial Organic Acids Test indicated yeast and/or bacterial overgrowth? Have repeated courses of antibiotics and/or antifungals failed to resolve these often chronic disorders? Have you tried multiple probiotics which have failed to repopulate the gut with good bacteria and yeast? Has IgG food allergy testing shown continued food allergies despite removal of the common allergens like wheat, dairy, and soy? Has your patient developed new or increasing food allergies despite being on an “allergy-friendly” diet? If you answered yes to any of these questions, considering a more specific and restrictive diet beyond GFCF (Gluten Free, Casein Free) could be the next step in healing for your patients.":1,"#Special diets have become increasingly common and more popular in recent years. Reports from both physicians and patients, many with laboratory tests confirming, say they can be helpful for a variety of diseases including autism, ADHD, multiple sclerosis, auto-immunity, rheumatoid arthritis, bowel conditions, and many more. Three diets in particular appear to help address gut dysbiosis, the overgrowth of microbes such as yeast and bacteria, which can be problematic for many individuals. Research shows that more than 70% of children with an Autism Spectrum Disorder (ASD) report a history of GI complaints.1 “Leaky Gut”, or intestinal permeability, results from larger than normal spaces between the cells of the gut wall. These spaces allow undigested food and toxins to enter the blood stream. When this happens, the immune system can mount an attack against the foreign particles which may result in food sensitivities and/or allergies. When the offending foods are eaten again, the release of antibodies triggers inflammation. This chronic inflammation further exacerbates the cycle by lowering Immunoglobulin A (IgA) levels. Adequate IgA levels are required to protect the intestinal tract from the gut pathogens such as clostridia and yeast. This continuous cycle can increase gut dysbiosis and negatively impact the overall health of your patients. All three of these special diets – SCD, GAPS, and Paleo may help address these issues by reducing the amount of undigested and allergenic foods being consumed and healing both the gut and brain.":1,"#Diet can be a very effective way to reduce harmful gut pathogens by removing their food supply and decreasing the inflammation they cause. Diligence, dedication, and strict adherence is required from your patients to see the full benefits of these special diets. In cases where antibiotics, antifungals, supplements, and probiotics have not been successful, these diets may help reverse the gut dysbiosis, after which reintegrating various supplements and probiotics may be effective . For newly diagnosed patients, implementing one of these diets may be a good way to begin their healing process quickly and effectively. As Ann Wigmore, health practitioner, nutritionist, and whole foods advocate said, “The food you eat can be either the safest and most powerful form of medicine or the slowest form of poison”.":1,"#Neurotransmitter imbalances can cause or contribute to various issues such as anxiety, depression, poor sleep, attention and focusing problems. This lecture will discuss different markers in the neurotransmitter section of the Organic Acids Test. CLICK HERE TO SIGN UP":1,"#This webinar will provide a comprehensive overview of the neurotransmitter section of the Organic Acids Test (OAT). The OAT is a valuable tool for evaluating organic acid metabolites and assessing nutrient deficiencies that can impact brain function. The neurotransmitter section of the OAT provides a window into the brain’s health by measuring metabolites related to the production and metabolism of neurotransmitters. This webinar will explore the various neurotransmitter metabolites measured on the OAT and their significance in evaluating neurotransmitter balance and function. Attendees will gain a deeper understanding of how to interpret and apply the results of this section of the OAT in clinical practice.":1,"#In this article I highlight specific parasites often encountered in a general integrative and functional medicine clinical practice: <em ljsid-1=\"\">Blastocystis hominis, Cryptosporidium parvum, Dientamoeba fragilis, Entamoeba histolytica, </em>and <em ljsid-3=\"\">Giardia lamblia.</em>":1,"#Goldenseal is a perennial herb that flourishes in the eastern regions of the United States and Canada (southeastern). As an antimicrobial, an interesting characteristic is a proposed efflux pump inhibition effect (30). Efflux pumps are intracellular mechanisms of various organisms that allow it to excrete antimicrobial chemicals that are transported or diffuse into the cell. As an anti-parasitic botanical, Goldenseal appears to have activity against various protozoan parasites, including <em ljsid-1=\"\">Blastocystis hominis</em>, <em ljsid-3=\"\">Entamoeba histolytica</em>, and <em ljsid-5=\"\">Giardia lamblia</em> (31).":1,"#<em ljsid-0=\"\">Bilberry is an edible fruit from the plant species Vaccinium myrtillus</em>. The berry has similarities to the American blueberry and goes by various names such as “wimberry”, “wortleberry”, and European blueberry (27). Much of the beneficial effects of bilberry extract focus on its antioxidant and circulatory properties for improved cardiovascular function. However, the phenolic properties of bilberry extract are known to affect the growth of certain bacteria such as <em ljsid-2=\"\">Clostridia</em>and H. <em ljsid-4=\"\">pylori </em>(28). Because of its diverse nature, this botanical has also been shown to adversely affect various parasites like <em ljsid-6=\"\">Giardia</em> and <em ljsid-8=\"\">Cryptosporidium</em> (29).":1,"#Nitazoxanide is a broad-spectrum antibiotic primarily used for acute <em ljsid-1=\"\">Giardia</em> and <em ljsid-3=\"\">Cryptosporidium</em> infections, but it does have broader application as an anti-helminthic and antiviral (23, 24). Approved for generic use in the United States in 2020 (25), The availability of Alinia for more than just acute diarrheal disease from protozoal parasites has gained wide acceptance.":1,"#This antibiotic is commonly used for various parasitic infections, including <em ljsid-1=\"\">Giardia lamblia</em> and <em ljsid-3=\"\">Entamoeba histolytica</em>. It also has effectiveness against other pathogens such as <em ljsid-5=\"\">Fusabacteria</em>, <em ljsid-7=\"\">Bacteroides</em>, and <em ljsid-9=\"\">Clostridia difficile</em> (21, 22).":1,"#<strong ljsid-0=\"\">Blood smear</strong> – this method is important for blood-borne parasites like malaria (20) but is not useful for primary digestive system parasites like <em ljsid-2=\"\">Giardia lamblia</em> or <em ljsid-4=\"\">Cryptosporidium parvum.</em>":1,"#There is a significant difference in pathogenicity between <em ljsid-1=\"\">E. dispar</em> and <em ljsid-3=\"\">E. histolytica </em>with histolytica known to infect between 35 to 50 million people globally leading to more than 55,000 deaths annually (11). <strong ljsid-5=\"\"> </strong>":1,"#Organic acids testing is diagnostic tool that every healthcare practitioner should know about. Whether you are a family practitioner, psychiatrist, a nutritionist, or other type of practitioner, the information provided by organic acids testing can help identify underlying causes of a variety of chronic illnesses, including the symptoms of autism, neuropsychiatric disorders like depression and […]":1,"#Join us in this webinar as we explore the important link between chronic stress, adrenal insufficiency, and fatigue in autism and mental health disorders. We will dive into the impact of chronic stress on the adrenal glands, the role of adrenal hormones in regulating stress response, and how chronic stress can contribute to adrenal insufficiency and fatigue in individuals with autism and mental health disorders. Dr. Woeller shares insights from the latest research, case studies, and practical strategies for identifying and managing adrenal insufficiency and fatigue in these populations. Learn about evidence-based integrative approaches, including lifestyle modifications, nutritional interventions, and stress management techniques, that can support adrenal health and improve overall well-being for individuals with autism and mental health disorders. Don’t miss this opportunity to deepen your understanding of the complex interplay between chronic stress, adrenal insufficiency, and fatigue in these populations and gain practical tools to optimize care for your patients.":1,"#You searched for Stool - MosaicDX":1,"#<strong ljsid-0=\"\">Turnaround Time:</strong> Please Contact Customer Service for Estimate":1,"#Without a doubt, mycotoxins can be harmful to our health, especially if we are inundated with mold within closed home or office spaces. When it comes to food sources, however, questions arise as to whether certain foods should be eliminated to reduce exposure to mold, and if there are health implications to consuming foods with […]":1,"#Aflatoxin":1,"#It appears that some exposure to mycotoxins is almost inevitable, and a truly “low mycotoxin” or “low mold” diet would leave one with very few food options. Before embarking on a project to eliminate mold exposure from food, it is imperative to take in the entire clinical picture as individual reactions vary widely. Ranges for potential exposure have been developed based on available data and clinical observation. However, it is necessary to consider a person’s; age, body composition, nutrient status, comorbidities, allergen sensitivities, genetics, current toxin burden, the effect of a combination of different mycotoxins, etc., etc., as all have shown to impact the severity of symptoms and their progression. A look into the literature suggests that some diseases may be associated with food mycotoxins, but the evidence is incredibly difficult to assess over a lifetime. For example, epidemiological studies have shown correlations with increased incidence of hepatic carcinoma in populations with higher dietary aflatoxin exposure in addition to diagnosis of hepatitis B. An overall strategy, particularly for high-risk populations may involve reducing or removing foods, likely to have fungal contamination, with the clear understanding that individual response to mycotoxin exposure is not predictable.":1,"#2 – 4 mg/kg * (Max allowed set by FDA)":1,"#February 24, 2021":1,"#Zearalenone":1,"#Patulin":1,"#. 26. „Verrucarin A (T3D3720).“ T3DB,":1,"#. 23. Riaz, Sana. „Cholestyraminharz.“ StatPearls [Internet]., US National Library of Medicine, 25. Mai 2020,":1,"#* Available in English, Spanish":1,"#THE MOST COMMON CHEMICAL TOXICANTS MEASURED BY THE GPL-TOX PROFILE In this blog, Dr. Joseph Pizzorno, ND, summarizes the GPL-TOX Profile’s compounds that are found most frequently at high levels. The GPL-TOX Profile quantifies the most widespread human-made toxic compounds, including acrolein, acrylamide, bromopropane, MTBE, and perchlorate, followed by phthalates, styrene, and xylene. Dr. Pizzorno […]":1,"#Join us live online on June 7th for Discovering the Power of the Organic Acids Test. By signing up for MosaicDX’s one-day seminars, you’ll gain a comprehensive understanding of the fundamentals of the Organic Acids Test, covering topics like OAT interpretation, clinical application, and applying disease conditions and OAT patterns. Our seminars are designed to provide you […]":1,"#Join us live online on <strong ljsid-1=\"\">June 7th</strong> for <strong ljsid-3=\"\">Discovering the Power of the Organic Acids Test</strong>.":1,"#ein. Hefe":1,"#QUELLE":1,"#Toxine":1,"#https://pubmed.ncbi.nlm.nih.gov/12588102":1,"#Lactobacillus-":1,"#Bazillusarten":1,"#May 25-26, 2024":1,"#Advanced Applications in Medical Practice (AAMP)":1,"#May 17-19, 2024 |":1,"#Integrative Health Symposium (IHS)":1,"#Exhibiting Only":1,"#February 15-17, 2024 |":1,"#Upcoming Conferences:":1,"#Attending conferences is a great way to connect, learn, and collaborate. Joining us at these events provide valuable insights, networking with fellow professionals, and a platform to stay updated on the latest trends and innovations. We look forward to connecting with you and sharing enriching experiences together. Upcoming Conferences: February 15-17, 2024 | Exhibiting OnlyIntegrative […]":1,"#Barcelona, Spain":1,"#ICNM International Congress on Naturopathic Medicine":1,"#July 5-7, 2024 |":1,"#Wellness Way Seminar – Leadership and Longevity":1,"#Attending conferences is a great way to connect, learn, and collaborate. Joining us at these events provide valuable insights, networking with fellow professionals, and a platform to stay updated on the latest trends and innovations. We look forward to connecting with you and sharing enriching experiences together.":1,"#Finalmente Focado":1,"#Join us live online on June 7th for Discovering the Power …":1,"#<strong ljsid-0=\"\">Figure 1</strong> – Child with high tartaric acid was started on the antifungal drug, Nystatin, and tested. Even after 68 days, tartaric increased when the dose was reduced in half and then decreased again when the full dose was restored.":1,"#GPL-TOX: Toxic Non-Metal Chemicals":1,"#<strong ljsid-0=\"\">Mycotoxin Properties and Metabolism, <a ljsid-0-1=\"\">Part 1</a> et <a ljsid-0-3=\"\">Part 2</a>.</strong> In any journey to understanding how our bodies process mycotoxins it is crucial to understand their metabolism. These blog posts describe the properties and metabolism of the mycotoxins analyzed by Mosaic Diagnostics.":1,"#Fungi, its role in Autism, and how we treat it? (الفطريات ودورها في التوحد…":1,"#Dr Amr Ashry, Role of Fungi in Autism (دور الفطريات في التوحد)":1,"#When it comes to mycotoxin binding research, we must keep in mind the toxic nature of these toxi…":1,"#In this insightful webinar, we delved into the clinical application of various genetic Single Nucleotide Polymorphisms (SNPs) in the DNA methylation pathway. Join Dr. Woeller as he discusses the role of DNA methylation in gene expression and its impact on health outcomes. Gain valuable insights into the clinical significance of specific SNPs in the DNA methylation pathway and how they can influence patient health and well-being. Discover practical strategies for incorporating DNA methylation testing and personalized interventions into your clinical practice. Stay up-to-date with the latest research, advancements, and clinical applications in the field of DNA methylation and genetic testing. Access the recorded session now to enhance your understanding of this important topic and optimize patient care. Don’t miss out on this informative webinar.":1,"#Depois de <a ljsid-1=\"\">abrir sua conta</a>, você terá a opção de solicitar kits para estocar em seu consultório ou enviar kits diretamente para seus pacientes através do portal <a ljsid-3=\"\">MosaicoDX</a> .":1,"#Go to page 21":1,"#Every day we are exposed to toxins from our environment. We may ingest lead and copper from drinking water, phosphate from processed food and soda, various synthetic chemicals from plastic food containers, and pesticides from fruits and vegetables. Both natural heavy metals and man-made chemicals disrupt hormones and brain development. The brain, especially the developing […]":1,"#Watch Dr. Neu’s Part 2 Presentation The material contained within this presentation is not intended to replace the services and/or medical advice of a licensed healthcare practitioner, nor is it meant to encourage diagnosis and treatment of disease. It is for educational purposes only. Any application of suggestions set forth in the following portions of […]":1,"#Posted on <time ljsid-1=\"\">October 27, 2023</time>":1,"#Watch Dr.Neu’s Part One Presentation The material contained within this presentation is not intended to replace the services and/or medical advice of a licensed healthcare practitioner, nor is it meant to encourage diagnosis and treatment of disease. It is for educational purposes only. Any application of suggestions set forth in the following portions of this […]":1,"#Posted on <time ljsid-1=\"\">November 17, 2023</time>":1,"#Több…":1,"#Bioidentical Hormone Replacement Therapy (BHRT) can be an effective method for replacing diminished sex hormones such as estrogen and testosterone. This lecture by Dr. Tracy Tranchitella will discuss modes of delivery (e.g. oral, transdermal), best absorption, follow-up testing and more. The full webinar can be viewed here: During the course of the Webinar, individuals were […]":1,"#Posted on <time ljsid-1=\"\">January 25, 2021</time>":1,"#Canadá Shipping Fees":1,"#At the end of the day, or end of history taking, the <a ljsid-1=\"\">Organic Acid Test</a> should be on the forefront of your mind as a practitioner. Really any client should be offered to take this worthwhile test. From your chronic disease patient to your “I just want to stay healthy” patient everyone will benefit. If you still find yourself asking “When do I run the OAT?” Keep in mind neurologic disease, autoimmune disease, chronic fatigue, pain, and autistic communities. In any case adding the OAT will be a benefit to anyone you offer it to.":1,"#Other circumstances can sometimes, let’s be honest, leave us feeling stuck as practitioners. After gathering all pertinent current and past medical history we find ourselves sometimes stumped. The person in front of us has a long history of many symptoms that can seem a mile, or two, long. This can be overwhelming, especially when they bring in completed traditional lab work that all reads normal or is well controlled on supplements or medication. Sometimes we ask ourselves, “Where do I start from here?” Often in these situations I find the OAT a great place to start. The way I describe the OAT is like a road map. This report will open new areas for you to stop and dig deeper. It will guide you in a direction you may have never thought to consider. Support also comes when it closes some doors that you’ve been considering or treating long term with little to no success. Profiling clients with the OAT gives you confirmation of your suspicions, new directions to consider, and an overall metabolic picture so you can support that person the way their body is asking to be supported.":1,"#When circumstances like these presents themselves, it is a great idea to add an OAT. Even if this is the only test you run, the information is invaluable. In some cases, I have seen results from people with no health complaints that showed increased mold growth or mitochondrial distress. Cases like these have helped with the prevention of disease. People were feeling well enough to test and remediate their home, then to undergo the detox protocol without a whole gambit of unfavorable symptoms. These are the cases where preventative medicine thrives. We should all be aiming to encourage clients to be proactive in their health and to get these wellness checks regularly so we don’t have to be reactive when disease arises.":1,"#Because the OAT is a metabolic profile, you don’t have to limit its use to only those that are not feeling well. Oftentimes, people find themselves curious about how healthy they are. They ask themselves: is a healthy diet, exercise, supplements, and meditation helping my body to work better? Am I really doing all I can to prevent disease? On the other hand, you have individuals who don’t necessarily incorporate healthy living habits and want to know where they stand. In some cases, you will have the client with an aged parent with a chronic disease and they want to understand what they can do to potentially prevent themselves from developing it.":1,"#So, as you can see the <a ljsid-1=\"\">Organic Acid Test</a> isn’t a test for only a handful of diagnoses and symptom pictures. It is a metabolic profile that helps us understand what is affecting the body and how we can metabolically respond. This helps us as practitioners to best support each client in their healing journey.":1,"#“The more you complete the OAT profile the more doors will be opened in the treatment and support of various conditions.”":1,"#I have also seen a handful of multiple sclerosis and ALS cases. In these cases, various causes and contributing factors have been alluded to and concluded using the OAT. Sometimes mold was the culprit, other times clostridia was involved. In some cases, chemicals and metals were the cause along with mitochondrial impairment. The more we do the OAT in complex diagnoses like these, the more we can make new connections that may not have been available before.":1,"#Other conditions that you can glean information from the <a ljsid-1=\"\">Organic Acid Test</a> include autoimmune conditions and dermatological complaints. I have seen various cases of eczema be healed as a result of information revealed in this profile. Often it was due to mold, candida, or other GI bacterial dysbiosis and overgrowth with poor detox abilities and nutritional deficiencies (2). One case showed elevated detox markers with no signs of mold or GI involvement. In this case the child was bathing in contaminated water by a toxin found on the <a ljsid-3=\"\">GPL-TOX Profile</a>. Marker 24 was elevated, and this led us to look at that report. Herpes virus recurrence was once a consequence of mold colonization found on the OAT. Hashimoto’s thyroiditis and a case of autoimmune alopecia in a child were well supported with the use of the OAT.":1,"#Autoimmune and Dermatological Conditions and the OAT":1,"#Under hypo-functioning states many neurologic conditions arise including Parkinson’s disease (5). Genetic polymorphisms in this enzyme’s functionality have been shown to contribute to the development of this diagnosis. DBH deficiency is also linked to Alzheimer’s, PTSD, ADHD, POTS, Depression, Autism (6), and schizophrenia (1). The presence of clostridia toxins in markers 15, 16, and 17 can also block DBH (6). Cases like this cause the same type of symptoms as the genetic disease. In relation to chronic pain, <a ljsid-1=\"\">oxalates are highly implicated</a>. Research has linked oxalates to vulvar pain syndrome as an irritant (4). Oxalate crystals also deposit in the joints and other tissues causing irritation and pain (3).":1,"#In neurologic conditions like Parkinson’s disease, the <a ljsid-1=\"\">Organic Acid Test</a> has shown itself to be helpful repeatedly. When viewing the neurotransmitter section, keep your eye on number 35, the HVA/VMA ratio. This marker assesses the function of the <a ljsid-3=\"\">Dopamine Beta Hydroxylase enzyme (DBH)</a>. This enzyme converts dopamine to norepinephrine/epinephrine.":1,"#Generalized malaise and fatigue along with chronic pain are conditions for which people often seek support.":1,"#Cognitive decline":1,"#Parkinson’s":1,"#Again and again, we’re asked: <em ljsid-1=\"\">What conditions are best supported by the OAT?</em> The fortunate news is OAT is beneficial to help diagnose numerous conditions. Because this is a metabolic profile, the results will show you how the person’s body is responding on a metabolic level to any condition they are suffering from. Whether it be a grouping of mysterious symptoms, a confirmed diagnosis of some sort, or a normal life phase like menopause, the OAT guides you in diagnosing and treating a wide range of conditions. To narrow things down there are a few conditions we often see well supported by using this report:":1,"#With all this information from one urine sample, how could you not consider assessing this profile for most of your clients. For more information on these sections review <a ljsid-1=\"\">10 Reasons To Do an Organic Acids Test</a> by Kurt Woeller, DO.":1,"#To begin, let’s understand why we should run the OAT. Let’s unpack its purpose and what information you will learn. At its core, the OAT is a metabolic profile that informs us about a wide range of body functions. Gastrointestinal fungal and bacterial overgrowth are assessed with specific <a ljsid-1=\"\">Clostridia</a> and mold biomarkers in the first section. Next oxalate formation and mitochondrial function are assessed. Then you get an understanding of neurotransmitter status. On page 4 of the OAT report, there is a comprehensive nutritional profile. Additionally, the indicators of detoxification section clue us into how well someone can handle their toxic burden.":1,"#This is a valid question as this profile can seem intimidating the first time you see it. With <a ljsid-1=\"\">Mosaic Diagnosics provided training</a> and supportive consults, the OAT is a useful tool for any client. In some cases, you’ll see a client with chronic disease that isn’t well supported with traditional therapies. Or maybe you will come across a client who you feel stumped on, or you feel uncertain or where to start your investigation of the root cause of disease. In other cases, you may have someone just looking to prevent disease that runs in their family. In any case, the OAT will shed light on the health situation at hand.":1,"#Since the creation of the <a ljsid-1=\"\">Organic Acid Test</a>, by William Shaw, PhD, many people have found answers to lingering health questions that could not otherwise be explained. To many seasoned and new practitioners, the wonders of the OAT have been known, but oftentimes practitioners still pose the question: <em ljsid-3=\"\">When should I run an OAT?</em>":1,"#July 25, 2022":1,"#The methylation cycle is an important biochemical system linked to brain, nervous system and immune function, cardiovascular health, energy production and detoxification. There are key components in the methylation cycle, that when damaged, can contribute to a host of chronic health disorders. This lecture will focus on the adverse effects certain toxins can cause with methylation. CLICK HERE TO SIGN UP":1,"#The Methylation Cycle is a crucial process in our body that is involved in numerous biochemical reactions. It regulates gene expression, neurotransmitter synthesis, hormone metabolism, and detoxification. However, toxins can interfere with this cycle, leading to adverse effects on our health. In this webinar, we will explore how toxins can disrupt the Methylation Cycle and the associated health consequences. We will discuss the role of different toxins, such as heavy metals, environmental chemicals, and mold toxins, in inhibiting key enzymes in the Methylation Cycle. We will also explore strategies to support Methylation Cycle function and enhance detoxification to mitigate the impact of toxins on our health. Join us to learn how to optimize your Methylation Cycle and safeguard your health from the harmful effects of toxins.":1,"#Q: I just returned overseas, have lived in Yangon, Myanmar, yeah our water heater was on the roof in our house too…":1,"#Q: How do you work with patients who live in other foreign countries? – lab testing? supplements?":1,"#May 5, 2021":1,"#Special diets have become increasingly common and more popular in recent years. Reports from both physicians and patients, many with laboratory tests confirming, say they can be helpful for a variety of diseases including autism, ADHD, multiple sclerosis, auto-immunity, rheumatoid arthritis, bowel conditions, and many more. Three diets in particular appear to help address gut […]":1,"#After a positive <a ljsid-1=\"\">Organische Säuren-Test</a> und <a ljsid-3=\"\">MycoTOX-Profil</a>, the presence of mold and mycotoxins are usually significant answers for many symptomatic clients. When working with mycotoxicosis, choosing the correct binder can present a challenge. Oftentimes I get the question: which binder is correct for which toxin? Since the research for the binding capacity of each binder isn’t as heavily researched as other agents, it can be daunting to sift through the information. Below is a collection of research connecting mycotoxins to a good binder choice.":1,"#Chronic Intestinal Candidiasis As A Possible Etiological Factor In The Chronic Fatigue Syndrome. - MosaicDX":1,"#In the spring and summer months, those of us who have lawns, enjoy time in the park, or even like a nice round of golf are typically in awe of how lush the grass and landscaping can be. This lusciousness can come with a price. In most cases pesticides, insecticides, herbicides, and fertilizers are used. […]":1,"#Posted on <time ljsid-1=\"\">September 8, 2021</time>":1,"#العنوان":1,"#. When the clock strikes 13, the accuracy of the other 12 hours of the clock is in serious question.":1,"#The tone for accuracy of the author is set in the very first paragraph of his article in which his first reference, #23, has nothing to do with my green smoothie article, which is reference #24. A better reference would actually be #2 from my article":1,"#2 – Inaccurate references.":1,"#1 – Cartoons about Popeye.":1,"#Response to Article on the Lack of Oxalate Dangers in the Green Smoothie Diet — Great Plains Laboratory":1,"#In response to the inaccurate, unscientific article by Thomas Lodi, M.D. on oxalates<sup ljsid-1=\"\">1</sup> in the December 2015 issue of Townsend Letter, I will make the following point-by-point responses:":1,"#A. J. Chaplin Histopathological occurrence and characterization of calcium oxalate: a review. J. Clin. Path., 1977, 30, 800-811":1,"#RI Levin, PW Kantoff and EA Jaffe Uremic levels of oxalic acid suppress replication and migration of human endothelial cells. Arterioscler Thromb Vasc Biol 1990, 10:198-207":1,"#Monica Eng, Chicago Tribune reporter. Soy in Illinois prison diets prompts lawsuit over health effects. December 21, 2009. http://articles.chicagotribune.com/2009-12-21/news/0912200121_1_soy-protein-soy-cheeses-soyfoods-association. Accessed December 2,2015":1,"#Solomons CC, Melmed MH, Heitler SM.Calcium citrate for vulvar vestibulitis. A case report. J Reprod Med. 1991 Dec;36(12):879-82.":1,"#Giuseppe Di Pasquale, , Mariangela Ribani, Alvaro Andreoli, , Gian Angelo Zampa, and Giuseppe Pinelli, Cardioembolic Stroke in Primary Oxalosis With Cardiac Involvement. Stroke 1989, 20:1403-1406":1,"#G.A. Fishbein, R. G. Micheletti, J. S. Currier, E. Singer, and M. C. Fishbein, Atherosclerotic oxalosis in coronary arteries, Cardiovascular Pathology, vol. 17, no. 2, pp. 117–123, 2008.":1,"#Jessica N. Lange, Kyle D.Wood, John Knight, Dean G. Assimos, and Ross P. Holmes. Glyoxal Formation and Its Role in Endogenous Oxalate Synthesis. Advances in Urology Volume 2012, Article ID 819202, 5 pages doi:10.1155/2012/819202":1,"#Kohmani,EF. Oxalic acid in foods and its fate in the diet. Journal of Nutrition 18(3):233-246,1939":1,"#Harvard T.H. Chan School of Public Health Nutrition Department’s File Download Site on oxalates in the diet. https://regepi.bwh.harvard.edu/health/Oxalate/files Accessed December 1,2015":1,"#Holmes RP, Goodman HO, and Assimos DG. Contribution of dietary oxalate to urinary oxalate excretion. Kidney International, Vol. 59 (2001), pp. 270–276":1,"#Shaw, W. The Green Smoothie Health Fad: This Road to Health Hell is Paved with Toxic Oxalate Crystals. Townsend Letter for Doctors. Jan 2015 Available online at: http://www.townsendletter.com/Jan2015/green0115.html":1,"#Lodi, T. Green smoothie bliss: Was Popeye secretly on dialysis? Townsend Letter for Doctors. Dec 2015 pgs 28-39":1,"#In summary, those who do not care for their health can eat or drink whatever they want. But they should realize that their diets are fad-based and/or based on quasi-religious (“feasts” as part of the “awakening” according to Lodi) reasons, not based on hard scientific evidence. Furthermore, they should be aware that their diet may kill them<sup ljsid-1=\"\">15</sup>. The green smoothie fad will go down in medical history with the AMA journal allowing cigarette advertising with physician endorsements and the use of mercury-containing teething powder for babies as one of the greatest health follies in a considerable time.":1,"#Primary genetic hyperoxaluria is not the major cause of kidney stones in adults since 80% of individuals died of this disorder before age 20 and it is so rare that it could not possibly be the cause of most cases of oxalate kidney stones<sup ljsid-1=\"\">13</sup>. However, a genetic polymorphism present in up to 20% of Caucasian groups called P11L codes for a protein with three times less activity of alanine: glyoxylate aminotransferase (AGT) than the predominant normal activity polymorphism, leading to excessive endogenous production of oxalates<sup ljsid-3=\"\">14</sup>. This substantial group of individuals would be even more susceptible to the harm of a high oxalate diet. Kidney stones were rampant in the United Kingdom during the World Wars when rhubarb, another high oxalate food, was recommended as a substitute for other low oxalate but unavailable vegetables<sup ljsid-5=\"\">13</sup>.":1,"#Furthermore, Lodi seems to think that a lack of kidney stones indicates a lack of oxalate problems. However, oxalates may form in virtually every organ of the body including the eyes, vulva, lymph nodes, liver, testes, skin, bones, gums, thyroid gland, heart, arteries, and muscles<sup ljsid-1=\"\">6-7</sup>. Oxalates may occur in these other organs without appearing in the urinary tract at all and in individuals without genetic hyperoxalurias<sup ljsid-3=\"\">7</sup>. Oxalates have been implicated in heart disease<sup ljsid-5=\"\">7</sup>, stroke, vulvodynia, and autism<sup ljsid-7=\"\">8-10</sup>. Women of child-bearing age need to be especially careful of the spinach green smoothie diet because of the autism oxalate connection and the negative effects of spinach containing oxalates on fertility<sup ljsid-9=\"\">5</sup>. Prisoners in the state prisons in Illinois were encouraged by the Weston-Price Nutrition Foundation to file a lawsuit against the state because of their deteriorating health due to a high amount of soy protein in the prison diet<sup ljsid-11=\"\">11</sup>. Soy protein is tied with spinach as the highest oxalate foods<sup ljsid-13=\"\">4</sup>. Oxalates are especially toxic to the endothelial cells of the arteries, leading to atherosclerosis<sup ljsid-15=\"\">12</sup>. Oxalate crystals are concentrated in the atherosclerotic lesions<sup ljsid-17=\"\">7</sup>. Such lesions have commonly been overlooked by the use of stains of atherosclerotic lesions that make the oxalate crystals difficult to visualize. The relatives of people consuming the green smoothie diet would only know of their loved ones’ oxalate deposits throughout their organs on the day of their autopsies which employed pathological examinations that can detect oxalates.":1,"#5 – Lodi argues that his patients haven’t complained about kidney stones while drinking a lot of green smoothies so oxalates must not be problematic.":1},"version":87919}]